{"id":4165,"date":"2016-11-06T21:20:26","date_gmt":"2016-11-06T21:20:26","guid":{"rendered":"http:\/\/doctorexpres.ro\/?p=4165"},"modified":"2016-11-06T21:21:29","modified_gmt":"2016-11-06T21:21:29","slug":"au-fost-descoperite-genele-care-controleaza-visele","status":"publish","type":"post","link":"http:\/\/doctorexpres.ro\/index.php\/2016\/11\/06\/au-fost-descoperite-genele-care-controleaza-visele\/","title":{"rendered":"Au fost descoperite genele care controleaz\u0103 visele"},"content":{"rendered":"

Analiz\u00eend creierul \u015fi activitatea genelor a mai mult de 8.000 de \u015foareci, cercet\u0103torii au identificat dou\u0103 gene care controleaz\u0103 somnul profund \u015fi visarea, deschiz\u00eend calea c\u0103tre noi tratamente pentru tulbur\u0103rile de somn.
\n\u00centr-un studiu publicat \u00een revista \u201eNature\u201d, oamenii de \u015ftiin\u0163\u0103 americani au anun\u0163at descoperirea unei gene care regleaz\u0103 num\u0103rul de mi\u0219c\u0103ri oculare rapide (REM), la mamifere, precum \u0219i a unei gene care controleaz\u0103 num\u0103rul de mi\u0219c\u0103ri oculare non-rapide din timpul somnului <\/a>(NREM).<\/p>\n

\u00cen conformitate cu National Sleep Foundation, REM este un stadiu de somn recurent, care ocup\u0103 circa 25% din somnul de noapte<\/a>. Implic\u0103 activitate cerebral\u0103 intens\u0103, care este comparabil\u0103 cu activitatea din starea de veghe a creierului. Visele cele mai intense apar, cel mai probabil, \u00een timpul somnului REM. NREM reprezint\u0103 75% din perioada de somn \u0219i se caracterizeaz\u0103 printr-o reducere a activit\u0103\u021bii cerebrale. Const\u0103 din trei etape: somnolen\u021b\u0103, somn u\u0219or \u0219i somn lent, cea mai ad\u00eenc\u0103 etap\u0103, \u00een care nu are loc nicio mi\u0219care a ochilor sau a musculaturii.
\nAt\u00eet REM c\u00eet si NREM s\u00eent considerate importante pentru s\u0103n\u0103tate, sprijinind dezvoltarea \u015fi repararea \u0163esuturilor, ajut\u00eend creierul \u015fi organismul s\u0103 func\u021bioneze \u00een mod eficient \u00een timpul zilei.<\/p>\n

Cu toate acestea, mecanismele care stau la baza regl\u0103rii ambelor faze de somn<\/a> s\u00eent neclare. Acum, pentru prima dat\u0103, cercet\u0103torii au identificat dou\u0103 gene care ar controla somnul REM \u015fi NREM.
\nPentru studiu, echipa prof. Joseph S. Takahashi, de la Institutul Brain O’Donnell al Universit\u0103\u0163ii din Texas, a introdus muta\u0163ii aleatorii la genele a mai mult de 8.000 de \u015foareci. S-a folosit electroencefalografia (EEG) pentru a monitoriza undele cerebrale ale roz\u0103toarelor, cu scopul de a vedea dac\u0103 muta\u0163iile le-au afectat somnul<\/a>.
\nCercet\u0103torii au identificat dou\u0103 gene, Sik3 \u0219i Nalcn, care par s\u0103 joace un rol \u00een REM \u0219i NREM. \u0218oarecii care au avut o mutatie a genei Sik3, numi\u0163i \u0219oareci \u201eadormi\u0163i\u201d, s-au dovedit a avea cu 50% mai mult somn NREM dec\u00eet \u015foarecii f\u0103r\u0103 aceast\u0103 muta\u0163ie.
\n\u201eAm observat c\u0103 mutan\u0163ii somnoro\u015fi au ar\u0103tat un r\u0103spuns exagerat la privarea de somn<\/a><\/em>\u201d, remarc\u0103 Hiromasa Funato, de la Universitatea din Tsukuba, Japonia. \u201eExaminarea creierului la \u015foarecii lipsi\u0163i de somn a dezv\u0103luit schimb\u0103ri, produse de muta\u0163ia Sik3, acesta fiind motivul pentru care \u015foarecii somnoro\u015fi au o nevoie crescut\u0103 de somn<\/a>.<\/em>\u201d \u00cen plus, s-a descoperit c\u0103 \u015foarecii cu o muta\u0163ie \u00een gena Nalcn, porecli\u0163i \u201enevis\u0103tori\u201d, s-au dovedit a avea mult mai pu\u021bin somn REM dec\u00eet \u015foarecii f\u0103r\u0103 aceast\u0103 muta\u0163ie genetic\u0103.
\n\u00cen concluzie, cercet\u0103torii cred c\u0103 aceste descoperiri sugereaz\u0103 c\u0103 Sik3 \u0219i Nalcn joac\u0103 un rol semnificativ \u00een somnul <\/a>mamiferelor.<\/p>\n

National Sleep Foundation recomand\u0103 ca adul\u0163ii cu v\u00eerste cuprinse \u00eentre 18-64 ani s\u0103 aib\u0103 circa 7-9 ore de somn pe zi, \u00een timp ce adul\u0163ii de peste 65 de ani ar trebui s\u0103 doarm\u0103<\/a> aproximativ 7-8 ore.<\/p>\n

Sursa: medicalnewstoday.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Analiz\u00eend creierul \u015fi activitatea genelor a mai mult de 8.000 de \u015foareci, cercet\u0103torii au identificat dou\u0103 gene care controleaz\u0103 somnul<\/p>\n","protected":false},"author":4,"featured_media":4166,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[96,818,88,91],"tags":[4932,4937,4938,4936,4931,4930,4935,4934,4933],"class_list":["post-4165","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-boli","category-creier-si-sistem-nervos","category-somnul-si-insomnia","category-stiri","tag-fazele-somnului","tag-genele-care-controleaza-somnul","tag-mecanismele-somnului","tag-nalcn","tag-nrem","tag-rem","tag-sik3","tag-somn-profund","tag-somnul-cu-vise"],"yoast_head":"\nAu fost descoperite genele care controleaz\u0103 visele - 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