{"id":4684,"date":"2016-12-13T20:41:12","date_gmt":"2016-12-13T20:41:12","guid":{"rendered":"http:\/\/doctorexpres.ro\/?p=4684"},"modified":"2016-12-13T20:41:12","modified_gmt":"2016-12-13T20:41:12","slug":"saliva-mai-puternica-decit-morfina","status":"publish","type":"post","link":"http:\/\/doctorexpres.ro\/index.php\/2016\/12\/13\/saliva-mai-puternica-decit-morfina\/","title":{"rendered":"Saliva, mai puternic\u0103 dec\u00eet morfina"},"content":{"rendered":"<p align=\"JUSTIFY\"><span style=\"font-family: Times new roman,serif;\"><span style=\"font-size: medium;\">Speciali\u015ftii francezi au identificat o molecul\u0103 \u00een <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/10\/11\/guma-de-mestecat-un-obicei-plin-de-e-uri\/\" target=\"_blank\">saliv\u0103<\/a>, la fel de eficace ca morfina asupra durerii postoperatorii, dar f\u0103r\u0103 efecte secundare. <\/span><\/span><!--more--><\/p>\n<p align=\"JUSTIFY\"><span style=\"font-family: Times new roman,serif;\"><span style=\"font-size: medium;\">Descoperit\u0103 \u00een 1861, morfina a devenit rapid indispensabil\u0103 \u00een spitale. Pacien\u0163ii s-au confruntat cu dureri tot mai mari, a\u015fa c\u0103 medicii au crescut doza, sporind riscul efectelor secundare grave precum confuzie, insuficien\u0163\u0103 respiratorie, cu poten\u021bial letal. Ca s\u0103 nu mai vorbim de faptul c\u0103 morfina d\u0103 <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/07\/19\/test-esti-dependent-de-exercitii-fizice\/\" target=\"_blank\">dependen\u0163\u0103<\/a>. <\/span><\/span><\/p>\n<p align=\"JUSTIFY\"><span style=\"font-family: Times new roman,serif;\"><span style=\"font-size: medium;\">Medicii francezi au descoperit o alternativ\u0103 la acest analgezic puternic, eficient\u0103 asupra durerii postoperatorii \u0219i prezent\u00eend avantajul de a nu produce efecte secundare. Totul a \u00eenceput \u00een 2003, c\u00eend Catherine Rougeot, cercet\u0103tor la Institutul Pasteur, a descoperit existen\u021ba unei molecule <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/08\/17\/un-analgezic-pentru-dureri-menstruale-inverseaza-pierderile-de-memorie\/\" target=\"_blank\">analgezic <\/a>la \u0219obolani: sialorfina. A \u00eenceput s\u0103 caute o molecul\u0103 similar\u0103 la om \u015fi a identificat-o \u00een cele din urm\u0103 \u00een <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/11\/21\/ai-simtit-vreodata-un-gust-metalic-in-gura\/\" target=\"_blank\">saliv\u0103<\/a>. Molecula se nume\u015fte opiorfin\u0103. La \u0219obolani, amelioreaz\u0103 durerea fizic\u0103 \u0219i cea legat\u0103 de <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/10\/24\/alimente-cu-efect-antiinflamator\/\" target=\"_blank\">inflama\u021bie<\/a>, fiind chiar mai puternic\u0103 dec\u00eet morfina: \u201e<em>1 miligram de opiorfin\u0103 pe kilogram corp a fost la fel de eficace ca 3-6 miligrame de morfin\u0103<\/em>\u201d, anun\u0163a Catherine Rougeot \u00een 2006. Dar, \u00eenainte de a testa opiorfina la om, a trebuit s\u0103 verifice gradul de siguran\u0163\u0103 al moleculei, numit\u0103 \u00een forma stabilizat\u0103, STR-324. \u201e<em>Opiorfina \u0219i STR-324 nu au niciun efect asupra <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/11\/25\/remedii-naturale-pentru-hipo-si-hipertensivi-ii\/\" target=\"_blank\">tensiunii arteriale<\/a> \u015fi respira\u0163iei, dar au acelea\u0219i propriet\u0103\u021bi analgezice ca morfina<\/em>\u201d, a rezumat dr. Philippe Sitbon, anestezist la Institutul Gustave Roussy (din apropierea Parisului) \u015fi co-autor al studiului. Mai mult, nu provoac\u0103 <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/09\/07\/dependenta-de-alcool-poate-fi-uitata\/\" target=\"_blank\">dependen\u021b\u0103<\/a>. <\/span><\/span><\/p>\n<p align=\"JUSTIFY\"><span style=\"font-family: Times new roman,serif;\"><span style=\"font-size: medium;\">Eficient la animale, cum ar fi \u0219obolanii, STR-324 ar trebui s\u0103 fie testat la om p\u00een\u0103 la sf\u00eersitul anului viitor. Cercet\u0103torii sper\u0103 c\u0103 aceast\u0103 molecul\u0103 poate ameliora \u015fi alte <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/12\/12\/o-compresa-pe-buric-te-poate-scapa-de-dureri-si-raceala\/\" target=\"_blank\">tipuri de durere<\/a>, cum ar fi cea neuropat\u0103, adesea dificil de calmat cu a<a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/10\/03\/analgezicele-cresc-riscul-de-insuficienta-cardiaca\/\" target=\"_blank\">nalgezice conven\u021bionale<\/a>. Sau ar putea fi benefic\u0103 pentru pacien\u021bii care sufer\u0103 de durere cronic\u0103 \u0219i prezint\u0103 efecte secundare semnificative asociate cu tratamentul.<\/span><\/span><\/p>\n<p align=\"JUSTIFY\"><span style=\"font-family: Times new roman,serif;\"><span style=\"font-size: medium;\">Sursa: <a href=\"http:\/\/www.sciencesetavenir.fr\/sante\/douleur-l-opiorphine-une-nouvelle-molecule-qui-remplacera-la-morphine_108833\" target=\"_blank\">sciencesetavenir.fr<\/a><\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Speciali\u015ftii francezi au identificat o molecul\u0103 \u00een saliv\u0103, la fel de eficace ca morfina asupra durerii postoperatorii, dar f\u0103r\u0103 efecte<\/p>\n","protected":false},"author":4,"featured_media":4685,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[1007,91],"tags":[5718,5720,5722,5719,5723,5724,5721,5727,5717,5728,5726,5725,5716],"class_list":["post-4684","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aparatul-digestiv","category-stiri","tag-analgezic-dependenta","tag-analgezic-din-saliva","tag-catherine-rougeot","tag-dependenta-morfina","tag-opiorfina","tag-opiorhin","tag-philippe-sitbon","tag-saliva","tag-saliva-morfina","tag-saliva-pentru-durere","tag-sialorfina","tag-sialorphin","tag-str-324"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.7 - 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