{"id":5818,"date":"2017-03-06T21:48:08","date_gmt":"2017-03-06T21:48:08","guid":{"rendered":"http:\/\/doctorexpres.ro\/?p=5818"},"modified":"2017-03-06T21:48:54","modified_gmt":"2017-03-06T21:48:54","slug":"de-ce-durerile-femeilor-sint-mai-mari","status":"publish","type":"post","link":"http:\/\/doctorexpres.ro\/index.php\/2017\/03\/06\/de-ce-durerile-femeilor-sint-mai-mari\/","title":{"rendered":"De ce durerile femeilor s\u00eent mai mari?"},"content":{"rendered":"

Creierul unei femei e mai activ \u00een regiunile implicate \u00een procesarea durerii fa\u021b\u0103 de cel al b\u0103rbatului, potrivit unui studiu recent.
\nFemeile sufer\u0103 de o inciden\u021b\u0103 mai mare a afec\u021biunilor inflamatorii dureroase, cum ar fi fibromialgia \u015fi osteoartrita<\/a>, spun cercet\u0103torii.
\nPotrivit unui studiu recent realizat de cercet\u0103torii de la Universitatea de Stat din Georgia, atunci c\u00eend microglia (celulele imune din creier) a fost blocat\u0103, r\u0103spunsul feminin la medicamente opioide pentru durere<\/a> a potrivit nivelurile de ameliorare a durerii cu cele observate, \u00een mod normal, la b\u0103rba\u0163i.<\/p>\n

De\u015fi morfina continu\u0103 s\u0103 fie unul dintre medicamentele<\/a> primare utilizate pentru tratamentul durerii severe<\/a> sau cronice, este adesea mai pu\u021bin eficient\u0103 la femei.<\/p>\n

\u201e\u00centr-adev\u0103r, ambele studii, clinic \u015fi preclinic, arat\u0103 c\u0103 femeile necesit\u0103 aproape de dou\u0103 ori mai mult\u0103 morfin\u0103 <\/a>dec\u00eet b\u0103rba\u0163ii pentru a produce ameliorarea comparabil\u0103 a dureri<\/em>i\u201d, a declarat dr. Hillary Doyle, de la Institutul de Neuro\u015ftiin\u0163e din Georgia. \u201eEchipa noastr\u0103 a examinat o poten\u021bial\u0103 explica\u021bie pentru acest fenomen, prin diferentele de sex din microglia creierului<\/a><\/em>\u201d.<\/p>\n

La indivizii s\u0103n\u0103to\u0219i, microglia sondeaz\u0103 creierul, caut\u0103 semne de infec\u021bie<\/a> sau de agen\u021bi patogeni. \u00cen absen\u0163a durerii, morfina este privit\u0103 ca un agent patogen, activeaz\u0103 celulele imune al creierului \u015fi provoac\u0103 eliberarea de substan\u0163e chimice inflamatorii<\/a>, cum ar fi citokinele.<\/p>\n

Pentru a testa modul \u00een care diferen\u021ba de sex afecteaz\u0103 efectul morfinei, Doyle a dat \u0219obolanilor<\/a> masculi \u0219i femele un medicament care inhib\u0103 activarea microgliei.<\/p>\n

\u201eRezultatele studiului au implica\u0163ii importante \u00een tratamentul durerii \u015fi sugereaz\u0103 c\u0103 microglia poate fi legat\u0103 de medicamente pentru \u00eembun\u0103t\u0103\u0163irea amelior\u0103rii durerii cu opiacee la femei<\/a><\/em>\u201d, a spus dr. Anne Murphy, co-autor al studiului.<\/p>\n

Constatarea c\u0103 microglia e mai activ\u0103 \u00een regiunile creierului implicate \u00een procesarea durerii poate contribui la g\u0103sirea unei explica\u0163ii pentru care ratele de inciden\u021b\u0103 pentru diferite sindroame dureroase cronice s\u00eent semnificativ mai mari la femei dec\u00eet la b\u0103rba\u021bi.
\nSursa: sciencedaily.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Creierul unei femei e mai activ \u00een regiunile implicate \u00een procesarea durerii fa\u021b\u0103 de cel al b\u0103rbatului, potrivit unui studiu<\/p>\n","protected":false},"author":4,"featured_media":5819,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[93,91],"tags":[7980,6559,7986,2092,7990,7989,7981,7978,7983,7991,7979,7982,7985,1886,7988,7987,7984],"class_list":["post-5818","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","category-stiri","tag-ameliorarea-durerii","tag-citokine","tag-dr-anne-murphy","tag-durere-cronica","tag-durere-severa","tag-durerea-la-femei","tag-dureri-inflamatorii","tag-fibromialgia","tag-hillary-doyle","tag-medicamente-opioide","tag-microglie","tag-morfina","tag-opiacee","tag-osteoartrita","tag-procesarea-durerii","tag-sindroame-dureroase-cronice","tag-tratamentul-durerii"],"yoast_head":"\nDe ce durerile femeilor s\u00eent mai mari? - Doctor Expres<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/doctorexpres.ro\/index.php\/2017\/03\/06\/de-ce-durerile-femeilor-sint-mai-mari\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"De ce durerile femeilor s\u00eent mai mari? - Doctor Expres\" \/>\n<meta property=\"og:description\" content=\"Creierul unei femei e mai activ \u00een regiunile implicate \u00een procesarea durerii fa\u021b\u0103 de cel al b\u0103rbatului, potrivit unui studiu\" \/>\n<meta property=\"og:url\" content=\"http:\/\/doctorexpres.ro\/index.php\/2017\/03\/06\/de-ce-durerile-femeilor-sint-mai-mari\/\" \/>\n<meta property=\"og:site_name\" content=\"Doctor Expres\" \/>\n<meta property=\"article:published_time\" content=\"2017-03-06T21:48:08+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2017-03-06T21:48:54+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/doctorexpres.ro\/wp-content\/uploads\/2017\/03\/477841546_XS.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"459\" \/>\n\t<meta property=\"og:image:height\" content=\"278\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Doctor Expres\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scris de\" \/>\n\t<meta name=\"twitter:data1\" content=\"Doctor Expres\" \/>\n\t<meta name=\"twitter:label2\" content=\"Timp estimat pentru citire\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"http:\/\/doctorexpres.ro\/index.php\/2017\/03\/06\/de-ce-durerile-femeilor-sint-mai-mari\/#article\",\"isPartOf\":{\"@id\":\"http:\/\/doctorexpres.ro\/index.php\/2017\/03\/06\/de-ce-durerile-femeilor-sint-mai-mari\/\"},\"author\":{\"name\":\"Doctor Expres\",\"@id\":\"https:\/\/doctorexpres.ro\/#\/schema\/person\/28f79c329d023ab5816a649c97121076\"},\"headline\":\"De ce durerile femeilor s\u00eent mai mari?\",\"datePublished\":\"2017-03-06T21:48:08+00:00\",\"dateModified\":\"2017-03-06T21:48:54+00:00\",\"mainEntityOfPage\":{\"@id\":\"http:\/\/doctorexpres.ro\/index.php\/2017\/03\/06\/de-ce-durerile-femeilor-sint-mai-mari\/\"},\"wordCount\":347,\"commentCount\":126,\"image\":{\"@id\":\"http:\/\/doctorexpres.ro\/index.php\/2017\/03\/06\/de-ce-durerile-femeilor-sint-mai-mari\/#primaryimage\"},\"thumbnailUrl\":\"http:\/\/doctorexpres.ro\/wp-content\/uploads\/2017\/03\/477841546_XS.jpg\",\"keywords\":[\"ameliorarea durerii\",\"citokine\",\"dr. 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