{"id":6775,"date":"2022-10-12T15:27:23","date_gmt":"2022-10-12T12:27:23","guid":{"rendered":"http:\/\/doctorexpres.ro\/?p=6775"},"modified":"2022-10-12T15:27:11","modified_gmt":"2022-10-12T12:27:11","slug":"diabetul-ar-putea-fi-tratat-cu-o-singura-injectie-pe-luna","status":"publish","type":"post","link":"http:\/\/doctorexpres.ro\/index.php\/2022\/10\/12\/diabetul-ar-putea-fi-tratat-cu-o-singura-injectie-pe-luna\/","title":{"rendered":"Diabetul ar putea fi tratat cu o singur\u0103 injec\u0163ie pe lun\u0103"},"content":{"rendered":"

O injec\u0163ie lunar\u0103 ar putea ajuta la controlul glucozei \u00een diabetul zaharat de tip 2, conform unui studiu publicat \u00een revista medical\u0103 Nature Biomedical Engineering. Aceste descoperiri au fost observate la primate.<\/p>\n

Cercet\u0103torii de la Duke University (SUA) au creat o nou\u0103 tehnologie care ar putea ajuta la controlul pe termen lung al nivelului glucozei, cu o singur\u0103 injec\u0163ie<\/a>, ceea ce \u00eenseamn\u0103 un avans terapeutic imens fa\u0163\u0103 de tratamentele actuale.<\/p>\n

Prin crearea unui mecanism de eliberare controlat\u0103 a medicamentului \u015fi optimizarea timpului s\u0103u de circula\u0163ie \u00een organism, aceast\u0103 nou\u0103 injec\u0163ie cu biopolimeri ar putea \u00eenlocui injec\u0163iile zilnice cu insulin\u0103, prin tratamente aplicate o dat\u0103 sau de dou\u0103 ori pe lun\u0103 de c\u0103tre persoanele cu diabet zaharat<\/a> de tip 2.<\/p>\n

Multe tratamente actuale pentru diabetul de tip 2 folosesc o molecul\u0103 de semnalizare numit\u0103 peptid-1 glucagon (GLP1) pentru a determina pancreasul s\u0103 elibereze insulin\u0103<\/a> pentru controlul glicemiei. Dar aceast\u0103 peptid\u0103 este eliminat\u0103 din organism rapid.<\/p>\n

Cercet\u0103torii au creat o tehnologie care \u00eembin\u0103 GLP1 cu o polipeptid\u0103 (ELP) sensibil\u0103 la elastin\u0103 \u015fi la c\u0103ldur\u0103, \u00eentr-o solu\u0163ie care poate fi injectat\u0103 \u00een piele. Solu\u0163ia reac\u0163ioneaz\u0103 la c\u0103ldura corpului, form\u00eend un \u201edepozit\u201d de gel biodegradabil, care elibereaz\u0103 lent medicamentul atunci c\u00eend se dizolv\u0103.<\/p>\n

Testat\u0103 pe animale, terapia a ajutat la controlul glucozei pe o durat\u0103 de p\u00een\u0103 la trei ori mai mare dec\u00eet tratamentele de pe pia\u0163\u0103. Cercet\u0103torii au descoperit c\u0103 formula optimizat\u0103 a \u00eembun\u0103t\u0103\u0163it nivelurile de glucoz\u0103 la maimu\u0163e pentru mai mult de 14 zile, dup\u0103 o singur\u0103 injec\u0163ie, timp \u00een care medicamentul se elibereaz\u0103 constant.<\/p>\n

\u201eAm demonstrat c\u0103 medicamentul ar putea dura mai mult de dou\u0103 s\u0103pt\u0103m\u00eeni la primate<\/em>\u201c\u201d, a declarat Kelli Luginbuhl, co-autor al studiului. \u201eDeoarece metabolismul nostru este mai lent dec\u00eet cel al maimu\u0163elor \u015fi \u015foarecilor, tratamentul ar trebui s\u0103 dureze mai mult, teoretic, chiar \u015fi la om. Sper\u0103m c\u0103 acest lucru va fi prima formul\u0103 bi-s\u0103pt\u0103m\u00eenal\u0103 sau lunar\u0103 pentru persoanele cu diabet zaharat <\/a>de tip 2<\/em>.\u201d<\/p>\n

Sursa: topsante.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

O injec\u0163ie lunar\u0103 ar putea ajuta la controlul glucozei \u00een diabetul zaharat de tip 2, conform unui studiu publicat \u00een<\/p>\n","protected":false},"author":4,"featured_media":6800,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[96,85,91],"tags":[9759,9763,6924,8073,9760,9762,59,9761,9765,504,9766,9764,9767,8604],"class_list":["post-6775","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-boli","category-diabetul","category-stiri","tag-biopolimeri","tag-controlul-glucozei","tag-diabet-de-tip-2","tag-elastina","tag-eliberare-controlata","tag-elp","tag-glicemie","tag-glp1","tag-injectie-cu-insulina","tag-insulina","tag-kelli-luginbuhl","tag-peptid-1-glucagon","tag-tratament-de-lunga-durata-diabet","tag-tratament-diabet"],"yoast_head":"\nDiabetul ar putea fi tratat cu o singur\u0103 injec\u0163ie pe lun\u0103 - 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