{"id":8039,"date":"2022-09-23T10:06:06","date_gmt":"2022-09-23T07:06:06","guid":{"rendered":"http:\/\/doctorexpres.ro\/?p=8039"},"modified":"2022-09-23T10:06:02","modified_gmt":"2022-09-23T07:06:02","slug":"medicamentele-mai-ieftine-ni-se-par-mai-lipsite-de-efecte-secundare","status":"publish","type":"post","link":"http:\/\/doctorexpres.ro\/index.php\/2022\/09\/23\/medicamentele-mai-ieftine-ni-se-par-mai-lipsite-de-efecte-secundare\/","title":{"rendered":"Medicamentele mai ieftine ni se par mai lipsite de efecte secundare"},"content":{"rendered":"<p style=\"text-align: justify;\" align=\"JUSTIFY\">Platind un pre\u021b mai mare, sim\u021bi\u021bi c\u0103 lucrul cump\u0103rat este mai rapid, mai puternic, mai moale sau mai curat. \u0218ti\u021bi c\u0103 prima pe care a\u021bi pl\u0103tit-o merit\u0103. Dar c\u00eend vine vorba de medica\u021bie, un <a href=\"http:\/\/doctorexpres.ro\/index.php\/2017\/02\/12\/mii-de-medicamente-contin-un-colorant-periculos\/\" target=\"_blank\" rel=\"noopener noreferrer\">medicament<\/a> perceput a fi scump a fost asociat cu mai multe efecte <a href=\"http:\/\/doctorexpres.ro\/index.php\/2017\/08\/07\/scoarta-de-pin-maritim-o-aspirina-fara-efecte-secundare\/\" target=\"_blank\" rel=\"noopener noreferrer\">secundare<\/a> negative. Aceasta este constatarea unui nou studiu publicat \u00een revista Science.<!--more--><\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\">A\u021bi auzit de efectul placebo, nu? Da\u021bi cuiva o pastil\u0103 de zah\u0103r, spune\u021bi-i c\u0103 este <a href=\"http:\/\/doctorexpres.ro\/index.php\/2017\/05\/16\/aspirina-ajuta-fasolea-sa-reziste-secetei\/\" target=\"_blank\" rel=\"noopener noreferrer\">aspirin\u0103<\/a>, iar dac\u0103 spune c\u0103 se simte mai bine, probabil l-a ajutat efectul placebo. F\u0103c\u00eend nimic, de fapt, func\u021bioneaz\u0103, iar oamenii de \u0219tiin\u021b\u0103 studiaz\u0103 efectul placebo pentru a debloca farmacia intern\u0103 a creierului \u0219i pentru a \u00eencuraja vindecarea f\u0103r\u0103 a folosi <a href=\"http:\/\/doctorexpres.ro\/index.php\/2017\/08\/08\/nu-luati-medicamente-cu-suc-de-grepfruit\/\" target=\"_blank\" rel=\"noopener noreferrer\">medicamente<\/a> reale.<\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\"><a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/11\/02\/placeboterapia-trucul-care-pacaleste-boala\/\" target=\"_blank\" rel=\"noopener noreferrer\">Efectul placebo<\/a> are de asemenea un geam\u0103n: efectul nocebo. D\u00eendu-i prietenului t\u0103u o pastil\u0103 cu <a href=\"http:\/\/doctorexpres.ro\/index.php\/2017\/03\/10\/6-adevaruri-negre-despre-zaharul-alb\/\" target=\"_blank\" rel=\"noopener noreferrer\">zah\u0103r<\/a> care \u015ftie c\u0103 \u00eei face r\u0103u, aceasta \u00eel va face s\u0103 se simt\u0103 mai r\u0103u. Nu exist\u0103 nicio posibilitate ca o pastil\u0103 inactiv\u0103 s\u0103 intensifice <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/12\/14\/te-doare-ficatul-ce-ar-putea-sa-insemne\/\" target=\"_blank\" rel=\"noopener noreferrer\">durerea<\/a>, dar el totu\u0219i o va asocia cu disconfortul. Alexandra Tinnermann \u0219i colegii au analizat mai atent acest efect \u0219i au \u00eencercat s\u0103 \u00een\u021beleag\u0103 modul \u00een care mintea influen\u021beaz\u0103 sensibilitatea noastr\u0103 fa\u021b\u0103 de <a href=\"http:\/\/doctorexpres.ro\/index.php\/2017\/10\/05\/ce-poate-insemna-durerea-abdominala-in-partea-dreapta\/\" target=\"_blank\" rel=\"noopener noreferrer\">durere<\/a>.<\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\">Cercet\u0103torii au testat pe 49 de persoane eficacitatea a dou\u0103 creme anti-m\u00eenc\u0103rime: una cu ambalaj cu aspect scump \u0219i alta\u00a0 cu un ambalaj portocaliu, cu aspect ieftin. Cremele erau identice \u0219i niciuna nu con\u021binea ingrediente active.<\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\">Cercet\u0103torii au spus tuturor c\u0103 aceste creme au fosta sociate cu o sensibilitate crescut\u0103 la durere. Jum\u0103tate dintre participan\u021bi au fost informa\u021bi c\u0103 au primit crema \u201escump\u0103\u201d, celorlal\u0163i li s-a spus c\u0103 au primit crema \u201eieftin\u0103\u201d. Apoi, cercet\u0103torii au pus crema pe antebra\u021b \u0219i au aplicat c\u0103ldur\u0103 pentru a provoca un disconfort u\u0219or.<\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\">Toat\u0103 lumea avea aceea\u0219i crem\u0103 ineficient\u0103, dar cei c\u0103rora li s-a administrat crema \u201escump\u0103\u201d au raportat o mai mare sensibilitate la testul de c\u0103ldur\u0103, iar efectul nocebo a crescut \u00een timp, \u00een acest grup. \u201e<em>Cea mai probabil\u0103 explica\u0163ie este c\u0103 participan\u0163ii deduc c\u0103 <a href=\"http:\/\/doctorexpres.ro\/index.php\/2017\/08\/01\/medicamentele-pe-care-le-iau-pietonii-pot-provoca-accidente-rutiere\/\" target=\"_blank\" rel=\"noopener noreferrer\">medicamentele<\/a> scumpe con\u0163in un agent mai puternic \u015fi mai eficient \u015fi, prin urmare, produce mai multe <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/10\/31\/acupunctura-reduce-tensiunea-arteriala-eficient-si-fara-efecte-secundare\/\" target=\"_blank\" rel=\"noopener noreferrer\">efecte secundare<\/a><\/em>\u201d, au scris cercet\u0103torii \u00een studiul lor.<\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\">Testul cu unguentul a fost doar jum\u0103tate din experiment. Cercet\u0103torii au dezvoltat \u015fi o tehnic\u0103 RMN care m\u0103soar\u0103 activitatea simultan\u0103 a cortexului, trunchiului cerebral \u0219i a m\u0103duvei spin\u0103rii. Practic, ei puteau monitoriza \u00eentregul sistem de procesare a <a href=\"http:\/\/doctorexpres.ro\/index.php\/2017\/09\/11\/sciatica-durerea-crunta-pe-un-picior\/\" target=\"_blank\" rel=\"noopener noreferrer\">durerii<\/a> din organism, pentru a vedea cum mintea a afectat senza\u021bia de<a href=\"http:\/\/doctorexpres.ro\/index.php\/2017\/10\/09\/capsunele-reduc-durerile-de-genunchi\/\" target=\"_blank\" rel=\"noopener noreferrer\"> durere<\/a>. Au observat c\u0103 por\u021biuni ale m\u0103duvei spin\u0103rii au fost activate \u00een timpul afect\u0103rii nocebo \u0219i au descoperit dou\u0103 regiuni ale creierului legate de percep\u021bia pre\u021burilor \u0219i senza\u021biile alterate. Ei nu \u0219i-au dat seama cum func\u021bioneaz\u0103 toate aceste procese, dar au ni\u0219te idei pe care le vor explora mai profund.<\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\">Efectele placebo \u0219i nocebo s\u00eent frecvente \u00een studiile clinice; uneori participan\u021bii chiar renun\u021b\u0103 la studii datorit\u0103 <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/08\/10\/o-fetita-va-salva-lumea-de-efectele-adverse-ale-medicamentelor\/\" target=\"_blank\" rel=\"noopener noreferrer\">efectelor secundare<\/a>, chiar dac\u0103 erau \u00een grupul de control. Nocebo \u0219i placebo, prin urmare, s\u00eent variabile puternice \u00een procesul de dezvoltare a <a href=\"http:\/\/doctorexpres.ro\/index.php\/2017\/10\/05\/57-din-medicamentele-pentru-cancer-sint-inutile\/\" target=\"_blank\" rel=\"noopener noreferrer\">medicamentelor<\/a>, \u00een\u021belegerea mecanismelor care stau la baza acestora put\u00eend ajuta cercet\u0103torii s\u0103 proiecteze mai bine experimentele sau chiar s\u0103 dezv\u0103luie noi modalit\u0103\u021bi de a gestiona durerea f\u0103r\u0103 a se baza pe un medicament.<\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\">Sursa: <a href=\"http:\/\/blogs.discovermagazine.com\/d-brief\/2017\/10\/05\/nocebo-effect-expensive\/#.Wd0Hg-QlGu0\" target=\"_blank\" rel=\"noopener noreferrer\">discovermagazine.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Platind un pre\u021b mai mare, sim\u021bi\u021bi c\u0103 lucrul cump\u0103rat este mai rapid, mai puternic, mai moale sau mai curat. \u0218ti\u021bi<\/p>\n","protected":false},"author":4,"featured_media":8040,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[96,806,91],"tags":[12038,2282,12035,5389,12041,12036,12037,12034,12039,11121,12040],"class_list":["post-8039","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-boli","category-psihologie","category-stiri","tag-alexandra-tinnermann","tag-cortex","tag-durere-placebo","tag-efecte-secundare","tag-eficienta-medicamentelor","tag-maduva-spinarii","tag-medicamente-scumpe","tag-nocebo","tag-perceperea-efectelor-medicamentelor","tag-placebo","tag-pretul-medicamentelor"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.7 - 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