{"id":2134,"date":"2023-10-08T22:08:28","date_gmt":"2023-10-08T19:08:28","guid":{"rendered":"http:\/\/doctorexpres.ro\/?p=2134"},"modified":"2023-12-18T01:57:50","modified_gmt":"2023-12-17T23:57:50","slug":"sa-slabesti-la-batrinete-nu-e-o-idee-buna","status":"publish","type":"post","link":"https:\/\/doctorexpres.ro\/index.php\/2023\/10\/08\/sa-slabesti-la-batrinete-nu-e-o-idee-buna\/","title":{"rendered":"S\u0103 sl\u0103be\u015fti la b\u0103tr\u00eene\u0163e nu e o idee bun\u0103"},"content":{"rendered":"<p style=\"text-align: justify;\" align=\"JUSTIFY\"><span style=\"font-family: Times New Roman,serif;\"><span style=\"font-size: medium;\"><span lang=\"ro-RO\">Cercet\u0103torii americani au g\u0103sit o asociere \u00eentre greutatea mai mic\u0103 \u015fi depozitele mai extinse de proteine beta-amiloid, specifice <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/08\/17\/un-analgezic-pentru-dureri-menstruale-inverseaza-pierderile-de-memorie\/\" target=\"_blank\" rel=\"noopener noreferrer\">bolii Alzheimer<\/a>, \u00een creierul <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/06\/16\/fibrele-vegetale-asigura-o-imbatrinire-sanatoasa\/\" target=\"_blank\" rel=\"noopener noreferrer\">persoanelor \u00een v\u00eerst\u0103<\/a>. Concluzia, publicat\u0103 \u00een Journal of Alzheimer&#8217;s Disease, a fost remarcat\u0103 \u00een special \u00een r\u00eendul persoanelor care prezint\u0103 varianta genei APOE4, recunoscut\u0103 pentru rolul ei \u00een cre\u015fterea riscului de A<a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/07\/14\/descoperire-revolutionara-vaccin-impotriva-dementei\/\" target=\"_blank\" rel=\"noopener noreferrer\">lzheimer<\/a>.<br \/>\n<\/span><\/span><\/span><!--more--><\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\"><span style=\"font-family: Times New Roman,serif;\"><span style=\"font-size: medium;\"><span lang=\"ro-RO\">\u201e<em>Un nivel ridicat al amiloidului cortical este considerat a fi prima etap\u0103 a formei preclinice a bolii Alzheimer, a\u015fa c\u0103 descoperirile noastre sugereaz\u0103 c\u0103 persoanele care s\u00eent subponderale mai t\u00eerziu \u00een via\u0163\u0103 ar putea prezenta un risc mai mare pentru aceast\u0103 boal\u0103<\/em>\u201d, a spus dr. Gad Marshall, autorul principal al raportului. \u201e<em>G\u0103sirea acestei asocieri \u00eent\u0103re\u015fte ideea c\u0103 a fi subponderal pe m\u0103sur\u0103 ce <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/06\/28\/o-gena-face-ca-unii-oamenii-sa-para-mai-batrini-decit-sint\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u00eemb\u0103tr\u00eene\u015fti<\/a> nu poate fi un lucru bun atunci c\u00eend vine vorba de s\u0103n\u0103tatea creierului t\u0103u<\/em>.\u201d<\/span><\/span><\/span><\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\"><span style=\"font-family: Times New Roman,serif;\"><span style=\"font-size: medium;\"><span lang=\"ro-RO\">Ipoteza actual\u0103 implic\u0103 trei etape. Indivizii din stadiul 1 s\u00eent cognitiv normali, dar au crescute depozitele de amiloid. \u00cen etapa 2, se adaug\u0103 dovezi de neurodegenerare, cum ar fi depozitele tau crescute sau pierderile caracteristice de \u021besuturi cerebrale, f\u0103r\u0103 simptome cognitive. Etapa 3 adaug\u0103 schimb\u0103ri cognitive care, de\u015fi se situeaz\u0103 \u00eenc\u0103 \u00een normalitate, indic\u0103 un declin pentru acel individ. <\/span><\/span><\/span><\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\"><span style=\"font-family: Times New Roman,serif;\"><span style=\"font-size: medium;\"><span lang=\"ro-RO\">Investiga\u021bia a explorat rela\u021bia dintre indicele de mas\u0103 corporal\u0103 (IMC) \u015fi nivelurile de beta-amiloid la pacien\u0163i cu v\u00eersta cuprins\u0103 \u00eentre 62 \u015fi 90 de ani, normali din punct de vedere cognitiv \u015fi cu o stare general\u0103 de s\u0103n\u0103tate bun\u0103. Cercet\u0103torii au descoperit c\u0103 un <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/07\/31\/cela-mai-cunoscute-diete-si-efectul-yo-yo\/\" target=\"_blank\" rel=\"noopener noreferrer\">IMC mai mic<\/a> a fost asociat cu o mai mare reten\u021bie a Pib, ceea ce indic\u0103 depozite mai extinse de amiloid \u00een creier. Asocia\u021bia a fost cea mai pronun\u021bat\u0103 \u00een cazul participan\u021bilor cu greutate normal\u0103, care au fost grupul cu cel mai mic IMC \u00een studiu. Analiza a relevat faptul c\u0103 asocierea dintre un IMC mai mic \u0219i o mai mare reten\u021bie a Pib a fost important\u0103 pentru persoanele cu varianta genei APOE4, asociat\u0103 unui risc crescut de <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/06\/20\/alzheimer-o-maladie-reversibila\/\" target=\"_blank\" rel=\"noopener noreferrer\">Alzheimer<\/a>.<\/span><\/span><\/span><\/p>\n<p style=\"text-align: justify;\">Cercet\u0103torii sper\u0103 c\u0103 studiile viitoare vor explica mecanismul din spatele acestei descoperiri. \u201e<em>O explica\u021bie probabil\u0103 pentru asociere este c\u0103 un IMC sc\u0103zut este un indicator pentru debilitate, un sindrom care implic\u0103 greutate redus\u0103, mi\u0219care lent\u0103 \u0219i pierderea de putere, care este cunoscut\u0103 ca fiind asociat\u0103 cu un risc de <a href=\"http:\/\/doctorexpres.ro\/index.php\/2016\/09\/03\/anticorp-care-vindeca-boala-alzheimer-in-stadiu-incipient\/\" target=\"_blank\" rel=\"noopener noreferrer\">Alzheimer<\/a><\/em>\u201d, spune expertul, profesor de neurologie la Harvard Medical School.<\/p>\n<p style=\"text-align: justify;\" align=\"JUSTIFY\"><span style=\"font-family: Times New Roman,serif;\"><span style=\"font-size: medium;\"><span lang=\"ro-RO\">Sursa: <a href=\"http:\/\/medicalxpress.com\/news\/2016-08-weight-late-life-alzheimer-disease.html\" target=\"_blank\" rel=\"noopener noreferrer\">medicalxpress.com<\/a><\/span><\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cercet\u0103torii americani au g\u0103sit o asociere \u00eentre greutatea mai mic\u0103 \u015fi depozitele mai extinse de proteine beta-amiloid, specifice bolii Alzheimer,<\/p>\n","protected":false},"author":4,"featured_media":2135,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[1318,91,103],"tags":[361,1819,1818],"class_list":["post-2134","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-siluete","category-stiri","category-varstnici","tag-alzheimer","tag-legatura-alzheimer-kilograme","tag-slabit-dupa-60-de-ani"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.7 - 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