{"id":4673,"date":"2023-03-01T16:32:07","date_gmt":"2023-03-01T14:32:07","guid":{"rendered":"http:\/\/doctorexpres.ro\/?p=4673"},"modified":"2023-03-01T16:33:00","modified_gmt":"2023-03-01T14:33:00","slug":"studiu-prin-post-celulele-canceroase-redevin-normale","status":"publish","type":"post","link":"https:\/\/doctorexpres.ro\/index.php\/2023\/03\/01\/studiu-prin-post-celulele-canceroase-redevin-normale\/","title":{"rendered":"Studiu: Prin post, celulele canceroase redevin normale"},"content":{"rendered":"

Cercet\u0103torii de la UT Southwestern Medical Center au constatat c\u0103 postul intermitent inhib\u0103 dezvoltarea \u0219i progresia celui mai frecvent tip de leucemie la copii, dar nu ajut\u0103 \u00eentr-un alt tip de cancer<\/a> al s\u00eengelui, care afecteaz\u0103 frecvent adul\u021bii. <\/span><\/span><\/p>\n

Dr. Chengcheng Zhang, profesor asociat de fiziologie \u015fi senior autor al studiului publicat online \u00een Nature Medicine, anun\u0163\u0103 \u015fi c\u0103 a identificat \u201emecanismul responsabil pentru r\u0103spunsurile diferite la tratamentul prin post<\/em>\u201d. <\/span><\/span><\/p>\n

S-a descoperit c\u0103 repausul alimentar inhib\u0103 ini\u021bierea \u0219i inverseaz\u0103 progresia a dou\u0103 subtipuri de leucemie acut\u0103 limfoblastic\u0103, cu celule B-ALL \u015fi T-ALL. Aceea\u0219i metod\u0103, nu a func\u0163ionat \u00een cazul leucemiei mieloide acute (LMA). <\/span><\/span><\/p>\n

ALL, cel mai frecvent tip de leucemie descoperite la copii, poate ap\u0103rea la orice v\u00eerst\u0103. Toate tratamentele curente s\u00eent eficiente \u00een cazul a aproximativ 90% din copii, dar mult mai rar la adul\u021bi. Cele dou\u0103 tipuri de leucemie provin din celule sanguine diferite ale m\u0103duvei osoase derivate. ALL afecteaz\u0103 celulele B \u015fi celulele T, care lupt\u0103 \u00eempotriva bolii. AML vizeaz\u0103 alte tipuri de celule albe din s\u00eenge, cum ar fi macrofagele \u0219i granulocitele. \u00cen ambele cazuri, ALL \u0219i LMA, celulele canceroase r\u0103m\u00een imature \u015fi prolifereaz\u0103 incontrolabil. Nu reu\u0219esc s\u0103 func\u021bioneze bine \u0219i \u00eenlocuiesc celulele sanguine s\u0103n\u0103toase, ceea ce duce la anemie<\/a> \u0219i infec\u021bie. De asemenea, se pot infiltra \u00een \u021besuturi. <\/span><\/span><\/p>\n

Cercet\u0103torii americani au \u00eencercat diferite planuri de restric\u021bie dietetic\u0103 la \u015foareci \u015fi au folosit proteine fluorescente verzi sau galbene pentru a urm\u0103ri celulele canceroase. <\/span><\/span><\/p>\n

\u201eSurprinz\u0103tor, am constatat c\u0103, \u00een modelele ALL, un regim const\u00eend din cicluri de \u0219ase zile de post<\/a>, urmate de o zi de hr\u0103nire a inhibat complet dezvoltarea cancerului<\/em>\u201d, a spus dr. Zhang. La sf\u00eer\u0219itul a \u0219apte s\u0103pt\u0103m\u00eeni, \u0219oarecii \u00eenfometa\u0163i nu au avut nicio celul\u0103 canceroas\u0103 <\/a>detectabil\u0103, comparativ cu o medie de aproape 68% celule canceroase<\/a> descoperite \u015foarecii care au primit m\u00eencare<\/span><\/span>. <\/span><\/span><\/p>\n

Roz\u0103toarele care au fost supuse unui repaus alimentar alternativ au avut reduceri dramatice \u00een procentul de celule canceroase <\/a>din maduva osoas\u0103 \u015fi splin\u0103 (care filtreaz\u0103 s\u00eengele), precum \u0219i un num\u0103r redus de celule albe din s\u00eenge. <\/span><\/span><\/p>\n

\u201e\u00cen plus, \u00een urma tratamentului de repaus alimentar<\/a>, splinele \u0219i ganglionii limfatici au fost similare ca m\u0103rime cu cele de la \u0219oarecii normali. Cu toate c\u0103 ini\u0163ial erau canceroase, cele c\u00eeteva celule fluorescente care au r\u0103mas dup\u0103 \u0219apte s\u0103pt\u0103m\u00eeni \u00een \u015foarecii \u00eenfometa\u0163i, p\u0103reau s\u0103 se comporte ca \u015fi cum ar fi celule normale. \u0218oarecii din grupul care a m\u00eencat normal au murit \u00een 59 de zile, \u00een timp ce 75% din \u015foarecii care n-au m\u00eencat au supravie\u0163uit, ajun\u00eend mai mult de 120 de zile, f\u0103r\u0103 semne de leucemie<\/em>\u201d. <\/span><\/span><\/p>\n

Cercet\u0103torii caut\u0103 acum modalit\u0103\u021bi alternative care s\u0103 mimeze postul<\/a>. <\/span><\/span><\/p>\n

Dat fiind faptul c\u0103 studiul nu a implicat tratamente cu medicamente<\/a>, doar post, cercet\u0103torii discut\u0103 cu clinicienii dac\u0103 regimul ar putea fi testat c\u00eet mai rapid \u00een studiile clinice pe om.<\/span><\/span><\/p>\n

Sursa: medicalxpress.com\/news<\/a><\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Cercet\u0103torii de la UT Southwestern Medical Center au constatat c\u0103 postul intermitent inhib\u0103 dezvoltarea \u0219i progresia celui mai frecvent tip<\/p>\n","protected":false},"author":4,"featured_media":4674,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[96,93,92,7868,95,1327,91],"tags":[5699,5700,441,5701,5697,5696,5709,3273,5698,5708,5695,5704,5702,5707,5706,5705,5703],"class_list":["post-4673","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-boli","category-cancer","category-inima-si-sistem-circulator","category-martie","category-nutritie","category-regimuri-alimentare","category-stiri","tag-all-celule-b","tag-all-celule-t","tag-anemie","tag-cancer-al-sangelui","tag-descoperire-leucemie","tag-granulocite","tag-leucemia-mieloida-acuta","tag-leucemie","tag-leucemie-copii","tag-lma","tag-macrofage","tag-postul-inhiba-cancerul","tag-postul-trateaza-cancerul","tag-regim-de-post","tag-repaus-alimentar","tag-restrictie-alimentara","tag-terapie-prin-post"],"yoast_head":"\nStudiu: Prin post, celulele canceroase redevin normale - 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