{"id":5199,"date":"2017-01-18T21:47:17","date_gmt":"2017-01-18T21:47:17","guid":{"rendered":"http:\/\/doctorexpres.ro\/?p=5199"},"modified":"2017-01-18T21:47:17","modified_gmt":"2017-01-18T21:47:17","slug":"o-enzima-din-drojdie-ar-putea-trata-leucemia","status":"publish","type":"post","link":"https:\/\/doctorexpres.ro\/index.php\/2017\/01\/18\/o-enzima-din-drojdie-ar-putea-trata-leucemia\/","title":{"rendered":"O enzim\u0103 din drojdie ar putea trata leucemia"},"content":{"rendered":"

Leucemia limfoblastic\u0103 acut\u0103 (ALL) este cea mai comun\u0103 form\u0103 de leucemie la copii, reprezent\u00eend aproximativ 3 din 4 cazuri \u00een Statele Unite ale Americii.<\/span><\/span><\/p>\n

\u00centr-un nou studiu, cercet\u0103torii dezv\u0103luie modul \u00een care un compus izolat din drojdia de bere poate ajuta la tratarea bolii, distrug\u00eend celulele leucemiei, f\u0103r\u0103 a afecta celulele s\u0103n\u0103toase. <\/span><\/span><\/p>\n

ALL, cunoscut\u0103 \u015fi sub numele de leucemie<\/a> limfocitar\u0103 acut\u0103, este un cancer care \u00eencepe \u00een limfobla\u015fti, care s\u00eent celule albe imature ale s\u00eengelui<\/a> din m\u0103duva osoas\u0103. Indivizii cu ALL fac prea mul\u0163i limfobla\u015fti, l\u0103s\u00eend prea pu\u0163in loc celulelor albe mature <\/span><\/span>s\u0103n\u0103toase, celulelor ro\u015fii \u015fi trombocitelor. Ca rezultat, persoanele s\u00eent predispuse la anemie<\/a> \u015fi infec\u0163ii. <\/span><\/span><\/p>\n

\u00cen timp ce copiii mai mici de 5 ani au cel mai mare risc, marea majoritate a deceselor de la boal\u0103 apar la adul\u0163i. \u00cen 2017, se estimeaz\u0103 c\u0103 vor fi aproximativ 5.970 de cazuri noi de ALL diagnosticate la copiii \u015fi adul\u0163ii din SUA \u015fi \u00een jur de 1.440 de decese cauzate de aceast\u0103 boal\u0103. <\/span><\/span><\/p>\n

Chimioterapia, transplantul de celule stem<\/a>, radioterapia, chirurgia, precum \u015fi medicamentele<\/a> specifice, pot fi, de asemenea, o op\u0163iune. <\/span><\/span><\/p>\n

Potrivit studiului al c\u0103rui co-autor e Gisele Monteiro, de la \u015ecoala de \u015etiin\u0163e Farmaceutice de la Universitatea din Sao Paulo, Brazilia, o enzim\u0103 izolat\u0103 din bacteriile<\/a> Escherichia coli \u015fi Erwinia chrysanthemi, numit\u0103 L-asparaginaz\u0103, a fost utilizat\u0103 \u00een tratamentul ALL timp de decenii, ob\u0163in\u00eendu-se rate ridicate de remisie. Monteiro constat\u0103 c\u0103 enzima<\/a> poate declan\u015fa r\u0103spunsuri imune, de la u\u015foare, la severe, la aproximativ 25% dintre pacien\u0163i. Ca atare, este necesar un produs biofarmaceutic mai pu\u0163in toxic pentru tratamentul ALL. <\/span><\/span><\/p>\n

\u00centr-un studiu publicat \u00een revista \u201eScientific Reports\u201d, Monteiro \u015fi echipa dezv\u0103luie modul \u00een care au izolat enzima L-asparaginaz\u0103 din Saccharomyces cerevisiae, mai frecvent cunoscut\u0103 sub numele de drojdie de panifica\u0163ie sau drojdie de bere<\/a>. <\/span><\/span><\/p>\n

Echipa a constatat c\u0103 L-asparaginaza ob\u0163inut\u0103 din drojdie a ucis aproximativ 70-80% din celulele cu cancer<\/a>, comparativ cu 90% pentru L-asparaginaza derivat\u0103 din E. coli, dar prima s-a dovedit mai pu\u0163in toxic\u0103 \u015fi mai sigur\u0103 pentru ALL. <\/span><\/span><\/p>\n

Articolul integral \u00een medicalnewstoday.com<\/a><\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Leucemia limfoblastic\u0103 acut\u0103 (ALL) este cea mai comun\u0103 form\u0103 de leucemie la copii, reprezent\u00eend aproximativ 3 din 4 cazuri \u00een<\/p>\n","protected":false},"author":4,"featured_media":5200,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[96,93,1356,92,91],"tags":[6724,5701,6730,6737,6728,2882,5125,6736,6732,6731,6733,5698,6726,6725,6727,6729,6735,6734,5134,3276,1023],"class_list":["post-5199","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-boli","category-cancer","category-imunitate","category-inima-si-sistem-circulator","category-stiri","tag-all","tag-cancer-al-sangelui","tag-cancer-copii","tag-celule-albe","tag-celule-albe-imature","tag-celule-rosii","tag-drojdie-de-bere","tag-drojdie-de-bere-pentru-leucemie","tag-erwinia-chrysanthemi","tag-escherichia-coli","tag-l-asparaginaza","tag-leucemie-copii","tag-leucemie-limfoblastica-acuta","tag-leucemie-limfocitara-acuta","tag-limfoblasti","tag-maduva","tag-molt4","tag-remisie-leucemie","tag-saccharomyces-cerevisiae","tag-tratament-leucemie","tag-trombocite"],"yoast_head":"\nO enzim\u0103 din drojdie ar putea trata leucemia - 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