{"id":6970,"date":"2017-06-23T18:51:48","date_gmt":"2017-06-23T18:51:48","guid":{"rendered":"http:\/\/doctorexpres.ro\/?p=6970"},"modified":"2017-06-23T18:51:48","modified_gmt":"2017-06-23T18:51:48","slug":"uleiul-de-masline-extra-virgin-dusmanul-bolii-alzheimer","status":"publish","type":"post","link":"https:\/\/doctorexpres.ro\/index.php\/2017\/06\/23\/uleiul-de-masline-extra-virgin-dusmanul-bolii-alzheimer\/","title":{"rendered":"Uleiul de m\u0103sline extra-virgin, du\u015fmanul bolii Alzheimer"},"content":{"rendered":"

Dieta mediteranean\u0103, bogat\u0103 \u00een alimente pe baz\u0103 de plante, este asociat\u0103 cu o varietate de beneficii pentru s\u0103n\u0103tate, printre care \u015fi o inciden\u021b\u0103 mai sc\u0103zut\u0103 a demen\u021bei. Acum, cercet\u0103torii de la \u015ecoala de Medicin\u0103 Lewis Katz de la Temple University au identificat un ingredient specific care protejeaz\u0103 \u00eempotriva declinului cognitiv<\/a>: uleiul de m\u0103sline extra-virgin, o component\u0103 major\u0103 a dietei mediteraneene.<\/p>\n

\u00centr-un studiu publicat online, cercet\u0103torii arat\u0103 c\u0103 un consum de ulei de m\u0103sline extra virgin protejeaz\u0103 memoria <\/a>\u0219i capacitatea de \u00eenv\u0103\u021bare \u0219i reduce formarea pl\u0103cilor de beta-amiloid \u0219i a aglomer\u0103rilor neurofibrilare \u00een creier<\/a>, markeri clasici ai bolii Alzheimer.<\/p>\n

Echipa a identificat, de asemenea, mecanismele care stau la baza efectelor protectoare ale uleiului de m\u0103sline extra virgin. \u201eAm constatat c\u0103 uleiul de m\u0103sline reduce inflama\u021bia creierului, dar cel mai important, activeaz\u0103 un proces cunoscut sub numele de autofagie<\/em>\u201d, a declarat cercet\u0103torul principal Domenico Pratic\u00f2. Autofagia este procesul prin care celulele se descompun \u0219i elimin\u0103 resturile \u0219i toxinele intracelulare, cum ar fi pl\u0103cile de amiloid \u0219i aglomer\u0103rile tau.<\/p>\n

Celulele creierului<\/a> de la \u0219oarecii hr\u0103ni\u021bi cu diete \u00eembog\u0103\u021bite cu ulei de m\u0103sline<\/a> extra virgin au avut niveluri mai ridicate de autofagie \u0219i niveluri reduse ale pl\u0103cilor de amiloid \u0219i tau fosforilat, substan\u021b\u0103 responsabil\u0103 de m\u0103nunchiurile de fibre \u00eencurcate, care s\u00eent suspectate c\u0103 ar contribui la disfunc\u021bia celulelor nervoase din creier.<\/p>\n

\u201eUleiul de m\u0103sline extra-virgin este mai bun dec\u00eet fructele \u0219i legumele \u00een monoterapie, iar gr\u0103simea vegetal\u0103 mononesaturat\u0103 este mai s\u0103n\u0103toas\u0103 dec\u00eet gr\u0103simile animale saturate<\/em>\u201d, spune dr. Pratic\u00f2.<\/p>\n

Pentru a investiga rela\u0163ia dintre uleiul de m\u0103sline extra-virgin \u015fi demen\u0163\u0103, Dr. Pratic\u00f2 \u015fi colegii s\u0103i au folosit un model bine stabilit de boal\u0103 Alzheimer. Animalele dezvolt\u0103 trei caracteristici cheie ale bolii: tulbur\u0103ri de memorie<\/a>, pl\u0103ci amiloid \u0219i ghemuri neurofibrilare.<\/p>\n

Cercet\u0103torii au \u00eemp\u0103r\u021bit \u015foarecii \u00een dou\u0103 grupe, una care a primit hran\u0103 \u00eembog\u0103\u021bit\u0103 cu ulei de m\u0103sline<\/a> extra virgin \u0219i una care a primit hran\u0103 obi\u015fnuit\u0103. Uleiul de m\u0103sline a fost introdus \u00een diet\u0103 atunci c\u00eend \u0219oarecii aveau \u0219ase luni, \u00eenainte ca simptomele bolii Alzheimer s\u0103 apar\u0103.<\/p>\n

La v\u00eersta de 9 luni \u0219i 12 luni, \u0219oarecii cu diet\u0103 \u00eembog\u0103\u021bit\u0103 cu ulei de m\u0103sline extra virgin<\/a> au rezolvat mult mai bine testele concepute pentru a evalua memoria de lucru, memoria spa\u021bial\u0103 \u0219i abilit\u0103\u021bile de \u00eenv\u0103\u021bare.<\/p>\n

Studiile de \u021besut cerebral din ambele grupuri de \u0219oareci au eviden\u021biat diferen\u021be dramatice \u00een aspectul \u0219i func\u021bia celulelor nervoase.<\/p>\n

\u201eUn lucru care a ie\u0219it imediat \u00een eviden\u021b\u0103 a fost integritatea sinaptic\u0103<\/em>\u201d. Integritatea conexiunilor dintre neuroni, cunoscute sub numele de sinapse, a fost conservat\u0103 la animale pe diet\u0103 cu ulei de m\u0103sline. \u00cen plus, s-a constatat o cre\u0219tere dramatic\u0103 a activ\u0103rii autofagiei celulelor nervoase, care a fost \u00een cele din urm\u0103 responsabil\u0103 de reducerea nivelurilor de pl\u0103ci amiloid \u0219i fosforilat tau.<\/p>\n

\u201eDatorit\u0103 activ\u0103rii autofagiei, memoria \u0219i integritatea sinaptic\u0103 s-au p\u0103strat, iar efectele patologice destinate \u00een mod obi\u0219nuit dezvolt\u0103rii bolii Alzheimer au fost semnificativ reduse. Aceasta este o descoperire foarte important\u0103 deoarece suspecteaz\u0103 c\u0103 o reducere a autofagiei marcheaz\u0103 \u00eenceputul bolii Alzheimer<\/a><\/em>.\u201d<\/p>\n

Dr. Pratic\u00f2 \u0219i colegii s\u0103i planific\u0103 s\u0103 investigheze efectele introducerii uleiului de m\u0103sline extra virgin \u00een dieta acelora\u0219i \u0219oareci, la v\u00eersta de 12 luni, c\u00eend au dezvoltat deja plachete \u0219i ghemuri neurofibrilare. \u201eDe obicei, atunci c\u00eend un pacient vine la medic pentru simptome de demen\u021b\u0103, boala este deja prezent\u0103<\/em>\u201d, a ad\u0103ugat dr. Pratic\u00f2. \u201eVrem s\u0103 \u015ftim dac\u0103 uleiul de m\u0103sline ad\u0103ugat mai t\u00eerziu \u00een diet\u0103 poate opri sau inversa boala Alzheimer<\/em>.\u201d<\/p>\n

Sursa: medicalxpress.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Dieta mediteranean\u0103, bogat\u0103 \u00een alimente pe baz\u0103 de plante, este asociat\u0103 cu o varietate de beneficii pentru s\u0103n\u0103tate, printre care<\/p>\n","protected":false},"author":4,"featured_media":6984,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[89,96,818,95,91,103],"tags":[361,5119,2967,2971,2378,10098,10103,10102,2196,10106,10104,10105,380,10099,10101,10100,64,4758],"class_list":["post-6970","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-alimente","category-boli","category-creier-si-sistem-nervos","category-nutritie","category-stiri","category-varstnici","tag-alzheimer","tag-autofagie","tag-beta-amiloid","tag-dementa","tag-dieta-mediteraneana","tag-domenico-pratico","tag-ghemuri-neurofibrilare","tag-grasime-vegetala","tag-inflamatia-creierului","tag-integritatea-sinapselor","tag-memoria-de-lucru","tag-memoria-spatiala","tag-memorie","tag-placi-de-amiloid","tag-prevenirea-dementei","tag-tau-fosforilat","tag-ulei-de-masline","tag-ulei-de-masline-extravirgin"],"yoast_head":"\nUleiul de m\u0103sline extra-virgin, du\u015fmanul bolii Alzheimer - 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