{"id":7038,"date":"2022-11-30T19:42:08","date_gmt":"2022-11-30T17:42:08","guid":{"rendered":"http:\/\/doctorexpres.ro\/?p=7038"},"modified":"2022-11-30T19:42:21","modified_gmt":"2022-11-30T17:42:21","slug":"anticorp-care-ajuta-pacientii-sa-lupte-cu-cancerul","status":"publish","type":"post","link":"https:\/\/doctorexpres.ro\/index.php\/2022\/11\/30\/anticorp-care-ajuta-pacientii-sa-lupte-cu-cancerul\/","title":{"rendered":"Anticorp care ajut\u0103 pacien\u0163ii s\u0103 lupte cu cancerul"},"content":{"rendered":"

Ad\u0103ugarea unui anticorp experimental la chimioterapia cu medicamentul rituximab pare s\u0103 restabileasc\u0103 capacitatea de anihilare a cancerului<\/a>, la anumi\u021bi pacien\u021bi cu leucemie cu rezisten\u021b\u0103 natural\u0103 la medicament, potrivit unui studiu realizat de cercet\u0103torii de la Duke Cancer Institute.<\/p>\n

Studiul, publicat \u00een revista PLOS ONE, a testat noul anticorp pe s\u00eengele a 11 pacien\u021bi cu leucemie<\/a> limfocitar\u0103 cronic\u0103 \u015fi pune bazele unui studiu clinic de faz\u0103 1, care va \u00eencepe anul viitor, viz\u00eend tumori solide avansate, inclusiv cancere <\/a>pulmonare, de s\u00een \u0219i de colon.<\/p>\n

\u201eAceast\u0103 lucrare se bazeaz\u0103 pe constat\u0103rile anterioare conform c\u0103rora unii pacien\u0163i s\u00eent rezisten\u0163i \u00een mod natural la chimioterapia cu rituximab<\/em>\u201d, a declarat autorul principal, dr. Edward F. Patz. \u201eMedicul ac\u021bioneaz\u0103 par\u021bial printr-un mecanism imunitar care determin\u0103 celulele canceroase<\/a> s\u0103 moar\u0103. La unii oameni, acest mecanism imunitar este dezactivat.\u201d<\/em><\/p>\n

\u00cen studiile anterioare, Patz \u015fi colegii au identificat un anticorp \u00eempotriva unei proteine numit\u0103 factor complement H, sau CFH, care lucreaz\u0103 pentru a proteja celulele. Echipa lui Patz a constatat c\u0103 persoanele care au anticorpul au o capacitate natural\u0103 de a lupta \u00eempotriva cancerului<\/a>, deoarece anticorpul opre\u0219te sistemul de securitate al unei celule canceroase \u0219i o face mai vulnerabil\u0103 la medicamente sau lupt\u0103tori imuni.<\/p>\n

Unul dintre medicamentele pe care acest anticorp<\/a> le-ar putea ajuta este rituximabul, care este utilizat pentru a trata leucemia<\/a>, dar la unii pacien\u021bi are un efect limitat. Pentru a testa aceast\u0103 abordare, cercet\u0103torii au stabilit mai \u00eent\u00eei dac\u0103 pacien\u0163ii cu leucemie au fost sensibili la rituximab, pe baza unei analize a leucocitelor din s\u00eenge. Zece dintre cei 11 pacien\u021bi nu r\u0103spundeau la rituximab.<\/p>\n

Dar c\u00eend anticorpul CFH experimental a fost ad\u0103ugat la rituximab, cinci din cei 11 pacien\u0163i (45%) au avut o cre\u015ftere semnificativ\u0103 a procesului de anihilare a celulelor canceroase<\/a>.<\/p>\n

\u201eAceasta este o abordare combinat\u0103 \u015fi se pare c\u0103 elimin\u0103 protec\u0163ia imunitar\u0103 a celulelor canceroase. Pacien\u021bii care au fost rezisten\u021bi la rituximab au devenit sensibili la rituximab<\/em>\u201d, a spus Patz.<\/p>\n

Sursa: medicalxpress.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Ad\u0103ugarea unui anticorp experimental la chimioterapia cu medicamentul rituximab pare s\u0103 restabileasc\u0103 capacitatea de anihilare a cancerului, la anumi\u021bi pacien\u021bi<\/p>\n","protected":false},"author":4,"featured_media":4660,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[96,93,1356,91],"tags":[10226,10225,1559,10224,5554,10222,10223,3277,10221,3276],"class_list":["post-7038","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-boli","category-cancer","category-imunitate","category-stiri","tag-anticorp","tag-capacitate-naturala-de-a-invinge-cancerul","tag-celule-canceroase","tag-cfh","tag-chimioterapie","tag-edward-f-patz","tag-factor-complement-h","tag-leucemie-limfocitara-cronica","tag-rituximab","tag-tratament-leucemie"],"yoast_head":"\nAnticorp care ajut\u0103 pacien\u0163ii s\u0103 lupte cu cancerul - Doctor Expres<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/doctorexpres.ro\/index.php\/2022\/11\/30\/anticorp-care-ajuta-pacientii-sa-lupte-cu-cancerul\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Anticorp care ajut\u0103 pacien\u0163ii s\u0103 lupte cu cancerul - Doctor Expres\" \/>\n<meta property=\"og:description\" content=\"Ad\u0103ugarea unui anticorp experimental la chimioterapia cu medicamentul rituximab pare s\u0103 restabileasc\u0103 capacitatea de anihilare a cancerului, la anumi\u021bi pacien\u021bi\" \/>\n<meta property=\"og:url\" content=\"https:\/\/doctorexpres.ro\/index.php\/2022\/11\/30\/anticorp-care-ajuta-pacientii-sa-lupte-cu-cancerul\/\" \/>\n<meta property=\"og:site_name\" content=\"Doctor Expres\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-30T17:42:08+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-11-30T17:42:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/doctorexpres.ro\/wp-content\/uploads\/2016\/12\/Cancer-cells.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"461\" \/>\n\t<meta property=\"og:image:height\" content=\"277\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Doctor Expres\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scris de\" \/>\n\t<meta name=\"twitter:data1\" content=\"Doctor Expres\" \/>\n\t<meta name=\"twitter:label2\" content=\"Timp estimat pentru citire\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/doctorexpres.ro\/index.php\/2022\/11\/30\/anticorp-care-ajuta-pacientii-sa-lupte-cu-cancerul\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/doctorexpres.ro\/index.php\/2022\/11\/30\/anticorp-care-ajuta-pacientii-sa-lupte-cu-cancerul\/\"},\"author\":{\"name\":\"Doctor Expres\",\"@id\":\"https:\/\/doctorexpres.ro\/#\/schema\/person\/28f79c329d023ab5816a649c97121076\"},\"headline\":\"Anticorp care ajut\u0103 pacien\u0163ii s\u0103 lupte cu cancerul\",\"datePublished\":\"2022-11-30T17:42:08+00:00\",\"dateModified\":\"2022-11-30T17:42:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/doctorexpres.ro\/index.php\/2022\/11\/30\/anticorp-care-ajuta-pacientii-sa-lupte-cu-cancerul\/\"},\"wordCount\":354,\"image\":{\"@id\":\"https:\/\/doctorexpres.ro\/index.php\/2022\/11\/30\/anticorp-care-ajuta-pacientii-sa-lupte-cu-cancerul\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/doctorexpres.ro\/wp-content\/uploads\/2016\/12\/Cancer-cells.jpg\",\"keywords\":[\"anticorp\",\"capacitate naturala de a invinge cancerul\",\"celule canceroase\",\"cfh\",\"chimioterapie\",\"Edward F. 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